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Palmetic Acid Increases Risk- During Viral Seasons

by in Health Tips 23/04/2020

By Prithu Nath

Fatty acid metabolism is closely related to influenza virus infection. Viruses assemble their membrane using the host’s unsaturated fatty acids, such as palmitic acid. The reported effects of lipids on immune functions provide a new insight into how dietary fatty acids might play a critical role in health and disease. Therefore Stop your Intake of foods containing high amounts of Palmitic Acid.

Palmitic acid is such an important fatty acid that our body has developed ways to produce it from other nutrients. This internal ‘control mechanism’ (de novo lipogenesis) ensures that the concentration of palmitic acid is kept relatively stable. If needed, our body can produce palmitic acid internally from other fatty acids, sugars, and alcohol and even from proteins. So Stop your intake of Sugars and Alcohol. Limit your Proteins to 10% of your Meal Intake. Limit your Carbohydrates to 15gms per meal. Stop of Limit Grains containing Sugars or Carbohydrates.

Increased Level of Palmitic Acid Found in Obese People

Palmitic acid (PA) is the most common long-chain SFA found in animals and is significantly increased in the plasma of obese people (Opie and Walfish, 1963) and in the brain of male mice following HFD consumption (Morselli et al., 2014b).

From: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, 2017

Foods High in Palmitic Acid that must be avoided, Serving  per 100000 mg

 

FOR THE TECHIES:

The spike protein hemagglutinin and the proton-channel M2 of the influenza virus are S-acylated at the cytoplasmic and transmembrane cysteine residues by palmitic acid [31, 49]. Virus particles containing hemagglutinin with removed palmitoylation sites revealed defects in replication and membrane fusion [50, 59]. Although loss of the palmitoylation site in M2 does not affect the production of virus particles, attenuation of virus infectivity was observed when mice were infected with viruses having non-palmitoylated M2 [4, 18]. Therefore, rapid replication of the H7N9 virus consumes a large amount of palmitic acid; this finding is consistent with our observation that the serum level of palmitic acid is significantly reduced during the early onset of disease. In our study, the condition of one patient with a continuous decrease of serum palmitic acid gradually worsened until death. While another patient with an increasing serum level of palmitic acid recovered. Restored serum level of palmitic acid may reflect virus elimination. Therefore, we propose that real-time tracking of the serum level of palmitic acid may predict the prognosis after influenza infection.

https://www.thelancet.com/article/S2352-3964(18)30226-3/fulltext

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